Regulation of expression of O6-methylguanine-DNA methyltransferase and the treatment of glioblastoma (Review). Cabrini G, Fabbri E, Lo Nigro C, Dechecchi MC, Gambari R. Int J Oncol. 2015 May 29. doi: 10.3892/ijo.2015.3026. Abstract O-6-methylguanine-DNA methyltransferase (MGMT) is an abundantly expressed nuclear protein dealkylating O6-methylguanine (O6-MG) DNA residue, thus correcting the mismatches of O6-MG with a thymine […]
Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter. Hannigan A, Smith P, Kalna G, Lo Nigro C, Orange C, O’Brien DI, Shah R, Syed N, Spender LC, Herrera B, Thurlow JK, Lattanzio L, Monteverde M, Maurer ME, Buffa FM, Mann J, Chu DC, West CM, Patridge […]
Cisplatin-based chemoradiation plus cetuximab in locally advanced head and neck cancer: a phase II clinical study. Merlano M, Russi E, Benasso M, Corvò R, Colantonio I, Vigna-Taglianti R, Vigo V, Bacigalupo A, Numico G, Crosetto N, Gasco M, Lo Nigro C, Vitiello R, Violante S, Garrone O. Ann Oncol. 2011 Mar;22(3):712-7. doi: 10.1093/annonc/mdq412. Epub 2010 […]