High frequency of complex TP53 mutations in CNS metastases from breast cancer. Posted on 17 dicembre 2014 High frequency of complex TP53 mutations in CNS metastases from breast cancer. Lo Nigro C, Vivenza D, Monteverde M, Lattanzio L, Gojis O, Garrone O, Comino A, Merlano M, Quinlan PR, Syed N, Purdie CA, Thompson A, Palmieri C, Crook T. Br J Cancer. 2012 Jan 17;106(2):397-404. doi: 10.1038/bjc.2011.464. Epub 2011 Dec 20.